Resources

Technical Information & Research

Looking for the latest information on LabDiet® publications, announcements and press releases? Our Resources section provides you with the most up-to-date content that you need to stay in tune with all the LabDiet® innovations. All links are pdfs

• PHYTOESTROGRENS

  THE FACTS ABOUT ISOFLAVONES: A LOOK AT THE BIG PICTURE

  Isoflavones, the most common form of phytoestrogens, are detectable in most all diets fed to laboratory animals. Isoflavones are not bad for animals; however more and more researchers need to verify the levels contained in the diets for specific study area. Before making your decision about isoflavones, there is more that you should know.

  FACTS ON ISOFLAVONES IN DIETS

  Click the link below to find information to assist you in making the correct choice for your lab animals.

  • Isoflavones (IF) are a common class of phytoestrogens. They are plant-derived compounds capable of estrogenic or antiestrogenic effects on the animals consuming them. Isoflavones are structural mimics of endogenous 17ß-estradiol (Seielstad, et al., 1995).
  • IFs are nothing new. As early as the 1920s, IFs were found to affect body metabolism and in the 1940s, IFs found in red clover were found to affect sheep fertility.
  • Since the early 1990s, with an increase in endocrine disruptor (ED) awareness, IFs have been identified as contributing factors that may affect the outcome of such studies.
  • In the lab community, some advocate feeding low IF diets to all of their animals. However, others feel the low IF diets should only be used where appropriate.
  • THE FACTS ABOUT ISOFLAVONES: A LOOK AT THE BIG PICTURE
• NUTRIENT & CONTAMINENT LEVELS

  Physiologically, rats are similar to other single-stomached animals, except for their lack of a gall bladder and their diffuse pancreas, an organ that is well-formed in other monogastric animals. Three bile ducts lead directly from the liver to the duodenum. The best research results are obtained from uniformly sized rats that are produced in closed colonies. By using rats from the same source you can ensure uniformity of size, good reproduction, and fewer genetic variations.

  Physiologically, rats are similar to other single-stomached animals, except for their lack of a gall bladder and their diffuse pancreas, an organ that is well-formed in other monogastric animals. Three bile ducts lead directly from the liver to the duodenum. The best research results are obtained from uniformly sized rats that are produced in closed colonies. By using rats from the same source you can ensure uniformity of size, good reproduction, and fewer genetic variations.

• INTAKE & BIOLOGICAL DATA

  Physiologically, rats are similar to other single-stomached animals, except for their lack of a gall bladder and their diffuse pancreas, an organ that is well-formed in other monogastric animals. Three bile ducts lead directly from the liver to the duodenum. The best research results are obtained from uniformly sized rats that are produced in closed colonies. By using rats from the same source you can ensure uniformity of size, good reproduction, and fewer genetic variations.

  Physiologically, rats are similar to other single-stomached animals, except for their lack of a gall bladder and their diffuse pancreas, an organ that is well-formed in other monogastric animals. Three bile ducts lead directly from the liver to the duodenum. The best research results are obtained from uniformly sized rats that are produced in closed colonies. By using rats from the same source you can ensure uniformity of size, good reproduction, and fewer genetic variations.

• TECHNICAL UPDATES

  Physiologically, rats are similar to other single-stomached animals, except for their lack of a gall bladder and their diffuse pancreas, an organ that is well-formed in other monogastric animals. Three bile ducts lead directly from the liver to the duodenum. The best research results are obtained from uniformly sized rats that are produced in closed colonies. By using rats from the same source you can ensure uniformity of size, good reproduction, and fewer genetic variations.

  Physiologically, rats are similar to other single-stomached animals, except for their lack of a gall bladder and their diffuse pancreas, an organ that is well-formed in other monogastric animals. Three bile ducts lead directly from the liver to the duodenum. The best research results are obtained from uniformly sized rats that are produced in closed colonies. By using rats from the same source you can ensure uniformity of size, good reproduction, and fewer genetic variations.

• BIBLIOGRAPHY

  Physiologically, rats are similar to other single-stomached animals, except for their lack of a gall bladder and their diffuse pancreas, an organ that is well-formed in other monogastric animals. Three bile ducts lead directly from the liver to the duodenum. The best research results are obtained from uniformly sized rats that are produced in closed colonies. By using rats from the same source you can ensure uniformity of size, good reproduction, and fewer genetic variations.

  Physiologically, rats are similar to other single-stomached animals, except for their lack of a gall bladder and their diffuse pancreas, an organ that is well-formed in other monogastric animals. Three bile ducts lead directly from the liver to the duodenum. The best research results are obtained from uniformly sized rats that are produced in closed colonies. By using rats from the same source you can ensure uniformity of size, good reproduction, and fewer genetic variations.